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Bernstein test

Acid perfusion test

The Bernstein test is a method to reproduce symptoms of heartburn. It is most often done with other tests to measure esophageal function.

How the Test is Performed

The test is done in a gastroenterology laboratory. A nasogastric (NG) tube is passed through one side of your nose and into your esophagus. Mild hydrochloric acid will be sent down the tube, followed by salt water (saline) solution. This process may be repeated several times.

You will be asked to tell the health care team about any pain or discomfort you have during the test.

How to Prepare for the Test

You will be asked not to eat or drink anything for 8 hours before the test.

How the Test will Feel

You may have a gagging feeling and some discomfort when the tube is put in place. The acid may cause symptoms of heartburn. Your throat may be sore after the test.

Why the Test is Performed

The test tries to reproduce symptoms of gastroesophageal reflux (stomach acids coming back up into the esophagus). It is done to see if you have the condition.

Normal Results

The test results will be negative.

What Abnormal Results Mean

A positive test shows that your symptoms are caused by esophageal reflux of acid from the stomach.

Risks

There is a risk of gagging or vomiting.

References

Kavitt RT, Vaezi MF. Diseases of the esophagus. In: Flint PW, Haughey BH, Lund V, et al, eds. Cummings Otolaryngology: Head & Neck Surgery. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 69.

Pandolfino JE, Kahrilas PJ. Esophageal neuromuscular function and motility disorders In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 43.

    • Stomach and stomach lining

      Stomach and stomach lining - illustration

      The stomach connects the esophagus to the small intestines and is where the majority of food digestion takes place.

      Stomach and stomach lining

      illustration

      • Stomach and stomach lining

        Stomach and stomach lining - illustration

        The stomach connects the esophagus to the small intestines and is where the majority of food digestion takes place.

        Stomach and stomach lining

        illustration

      Tests for Bernstein test

       

      Review Date: 12/1/2016

      Reviewed By: Subodh K. Lal, MD, gastroenterologist with Gastrointestinal Specialists of Georgia, Austell, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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